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Article

Increased HIV-DNA load in CCR5-negative lymphocytes without viral phenotypic change.

Virology - 10 Apr 2006

Pakarasang Maitree, Wasi Chantapong, Suwanagool Surapol, Chalermchockcharoenkit Amphan, Auewarakul Prasert

Abstract excerpt

We have previously described a selective increase in HIV-DNA content in CCR5-negative lymphocytes from late stage HIV-infected patients. Here, we show that this increase occurred even in the absence of viral phenotypic switching from CCR5- to CXCR4-tropic. This leads us to hypothesize that early and late CCR5-tropic viruses might be different in the ability to infect CCR5-low or -negative cells. We compared a set...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16412490
DOI: 10.1016/j.virol.2005.12.003

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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