Article
Multilocus analysis of SNP and metabolic data within a given pathway.
BMC genomics - 13 Jan 2006
Kristensen Vessela N, Tsalenko Anya, Geisler Jurgen, Faldaas Anne, Grenaker Grethe Irene, Lingjaerde Ole Christian, Fjeldstad Ståle, Yakhini Zohar, Lønning Per Eystein, Børresen-Dale Anne-Lise
Abstract excerpt
BACKGROUND: Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing human geneticists is the identification and characterization of susceptibility genes for common multifactorial diseases and their association to different quantitative phenotypic traits. RESULTS: Two types of...
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