Article
Electrophysiological characterization of three non-synonymous single nucleotide polymorphisms (R87Q, A251T, and P307S) found in hKv1.5.
Pflugers Archiv : European journal of physiology - 1 Jun 2006
Plante Isabelle, Fournier Dominique, Ricard Guylaine, Drolet Benoît, O'Hara Gilles, Champagne Jean, Mathieu Patrick, Baillot Richard, Daleau Pascal
Abstract excerpt
Non-synonymous single nucleotide polymorphisms (SNPs) in the KCNA5/hKv1.5 gene, which encodes for a voltage-gated K+ channel responsible for the I (Kur) current in the human atria, have been recently reported. To gain further knowledge on potential influence of hKv1.5 SNPs, we searched for their presence in a specific population of 96 French-Canadians and characterized electrophysiological properties of the...
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