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Article

Genetic alterations in primary glioblastomas in Japan.

Journal of neuropathology and experimental neurology - 1 Jan 2006

Fukushima Takao, Favereaux Alexandre, Huang Hervé, Shimizu Tsuneo, Yonekawa Yasuhiro, Nakazato Yoichi, Ohagki Hiroko

Abstract excerpt

Current knowledge of genetic alterations in glioblastomas is based largely on genetic analyses of tumors from mainly caucasian patients in the United States and Europe. In the present study, screening for several key genetic alterations was performed on 77 primary (de novo) glioblastomas in Japanese patients. SSCP followed by DNA sequencing revealed TP53 mutations in 16 of 73 (22%) glioblastomas and PTEN...

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Source

Identifiers

PMID: 16410744
DOI: 10.1097/01.jnen.0000196132.66464.96

Genes

EGFR
PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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