Article
Association of haptoglobin levels with age, parasite density, and haptoglobin genotype in a malaria-endemic area of Gabon.
The American journal of tropical medicine and hygiene - 1 Jan 2006
Fowkes Freya J I, Imrie Heather, Migot-Nabias Florence, Michon Pascal, Justice Anita, Deloron Phillipe, Luty Adrian J F, Day Karen P
Abstract excerpt
Haptoglobin (Hp) levels were investigated in relation to host genotype in a malaria-endemic area in Gabon. A cross-sectional study of 1-12-year-old children was conducted in the rainy season, a period of high malaria transmission, to examine this relationship. Variables that influenced Hp levels were Hp genotype, location, and age interacting with parasite density. At low parasite densities, there was a negative...
Topics
- Aging
- Animals
- Child
- Child, Preschool
- Cross-Sectional Studies
- Female
- Gabon
- Genotype
- Haptoglobins
- Humans
- Infant
- Malaria
- Male
- Parasitemia
- Plasmodium falciparum
