Article
Variations of the Amnionless gene in recurrent spontaneous abortions.
Molecular human reproduction - 1 Jan 2006
Kaare Milja, Painter Jodie N, Ulander Veli-Matti, Kaaja Risto, Aittomäki Kristiina
Abstract excerpt
Recurrent spontaneous abortions (RSA) are estimated to affect 0.5-1% of couples trying to have a child. The causes of RSA are unknown in the majority of cases. This study aimed to determine whether homozygous mutations in the AMN gene in a fetus cause spontaneous abortions in humans, as they are known to cause spontaneous abortions in mice. The study was conducted by screening 40 couples and 5 women with three or...
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