Article
Novel missense mutation in WNT6 in 100 couples with unexplained recurrent miscarriage.
Human reproduction (Oxford, England) - 1 Apr 2015
Zhang Yimei, Li Guangyu, Fan Yuanyuan, Cui Yuqian, Huang Sexin, Ma Jinlong, Yan Junhao, Chen Zi-Jiang
Abstract excerpt
STUDY QUESTION: Do mutations and/or polymorphisms in coding sequences in Wingless-Type MMTV Integration Site Family, Member 6 (WNT6) play a role in unexplained recurrent miscarriage (unexplained RM) in Chinese couples? SUMMARY ANSWER: We found four mutations in the coding sequences of WNT6 which appear to exist in a small proportion of Chinese women with unexplained RM. WHAT IS KNOWN ALREADY: WNT6 has been proved...
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