Article
A single nucleotide polymorphism of the apolipoprotein A-V gene -1131T>C modulates postprandial lipoprotein metabolism.
Atherosclerosis - 1 Nov 2006
Moreno Rafael, Perez-Jimenez Francisco, Marin Carmen, Moreno Juan Antonio, Gomez Purificación, Bellido Cecilia, Perez-Martinez Pablo, Jimenez-Gomez Yolanda, Fuentes Francisco Jose, Lopez-Miranda Jose
Abstract excerpt
The Apolipoprotein A-V (apoA-V) gene promoter polymorphism -1131T>C modulates triacylglycerol (TG) concentrations. We evaluate whether this polymorphism could be involved in the interindividual variability observed during postprandial lipemia. Fifty-one healthy apo E3E3 male volunteers [12 with -1131CC/CT genotype, and 39 with -1131TT genotype] underwent a Vitamin A fat-load test consisting of 1g of fat/kg body...
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