Article
Highly Signal-Responsive Gene Regulatory Network Governing Myxococcus Development.
Trends in genetics : TIG - 1 Jan 2017
Kroos Lee
Abstract excerpt
The bacterium Myxococcus xanthus undergoes multicellular development when starved. Thousands of cells build mounds in which some differentiate into spores. This remarkable feat and the genetic tractability of Myxococcus provide a unique opportunity to understand the evolution of gene regulatory networks (GRNs). Recent work has revealed a GRN involving interconnected cascades of signal-responsive transcriptional...
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