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Article

Low Correlation between MIC and Mutant Prevention Concentration

23 Dec 2005

Abstract excerpt

Soon after the term mutant prevention concentration (MPC) was coined to define the MIC of the least susceptible mutant subpopulation of a microbial culture (2), we noticed that MPCs and MICs correlated poorly (r2 = 0.39) for a set of closely related fluoroquinolones when determined with Mycobacterium smegmatis (9). Subsequently, isolated examples were described in which correlation was low for a variety of...

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Identifiers

PMID: 16377725
DOI: 10.1128/aac.50.1.403-404.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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