Article
Mutant prevention concentrations of ciprofloxacin for urinary tract infection isolates of Escherichia coli.
The Journal of antimicrobial chemotherapy - 1 Jun 2005
Marcusson Linda L, Olofsson Sara K, Komp Lindgren Patricia, Cars Otto, Hughes Diarmaid
Abstract excerpt
OBJECTIVES: To measure the mutant prevention concentration (MPC) of ciprofloxacin for a set of urinary tract infection (UTI) Escherichia coli isolates with different levels of susceptibility and determine whether MPC can be predicted from MIC. METHODS: MPC was defined as the lowest ciprofloxacin concentration that prevented the growth of resistant colonies when 10(10) bacteria were spread on solid medium and...
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