Article
Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology.
European journal of clinical pharmacology - 1 Jan 2006
Ferreira Paula M, Catarino Raquel, Pereira Deolinda, Matos Ana, Pinto Daniela, Coelho Ana, Lopes Carlos, Medeiros Rui
Abstract excerpt
INTRODUCTION: Besides human papillomavirus (HPV) infection, several cofactors are considered important for the development of cervical cancer (CC). Among these, tobacco smoke, other sexually transmitted diseases, inflammation and nutritional factors have been intensively described. CYP2E1 polymorphisms have been associated with the metabolization of several carcinogens, some of them considered risk factors for CC...
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