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Article

Urease produced by Coccidioides posadasii contributes to the virulence of this respiratory pathogen.

Infection and immunity - 1 Jan 2006

Mirbod-Donovan Fariba, Schaller Ruth, Hung Chiung-Yu, Xue Jianmin, Reichard Utz, Cole Garry T

Abstract excerpt

Urease activity during in vitro growth in the saprobic and parasitic phases of Coccidioides spp. is partly responsible for production of intracellular ammonia released into the culture media and contributes to alkalinity of the external microenvironment. Although the amino acid sequence of the urease of Coccidioides posadasii lacks a predicted signal peptide, the protein is transported from the cytosol into...

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Identifiers

PMID: 16369007
DOI: 10.1128/IAI.74.1.504-515.2006
PMCID: PMC1346605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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