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Article

Clonal History of Papillomavirus-Induced Dysplasia in the Female Lower Genital Tract

20 Dec 2005

Abstract excerpt

BACKGROUND: Dysplastic lesions of the vagina or the vulva often occur in women who have a previous history of cervical dysplasia. Most lesions in the female lower genital tract are induced by infections with high-risk oncogenic human papillomaviruses (HR-HPVs), including HPV16 and HPV18. HR-HPV genomes frequently integrate into host cell chromosomes at random sites. We analyzed viral integration sites in multiple...

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Identifiers

PMID: 16368943
DOI: 10.1093/jnci/dji428

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Source receipt: pubmed, retrieved 7 Sept 2026.

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