Article
Relationship between plasma HDL subclasses distribution and lipoprotein lipase gene HindIII polymorphism in hyperlipidemia.
Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2006
Long Shiyin, Tian Ying, Zhang Rong, Yang Luchuan, Xu Yanhua, Jia Lianqun, Fu Mingde
Abstract excerpt
BACKGROUND: Different high-density lipoprotein (HDL) subclasses have distinct but interrelated metabolic functions. HDL directly influences the atherogenic process, and changes in HDL subclasses distribution may be related to the incidence and prevalence of atherosclerosis. Lipoprotein lipase (LPL) is an important enzyme for hydrolysis of triglyceride-rich lipoproteins, and its activity is positively correlated...
Topics
- Adult
- Aged
- Alleles
- Analysis of Variance
- Apolipoprotein A-I
- Binding Sites
- Cholesterol
- Cholesterol, HDL
- Deoxyribonuclease HindIII
- Female
- Gene Frequency
- Genotype
- Humans
- Hyperlipidemias