Lipoprotein lipase HindIII polymorphism influences HDL-cholesterol levels in statin-treated patients with coronary artery disease.

doi:10.1007/s00508-007-0824-1

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Article

Lipoprotein lipase HindIII polymorphism influences HDL-cholesterol levels in statin-treated patients with coronary artery disease.

Wiener klinische Wochenschrift - 1 Jan 2007

Javorský Martin, Gasperíková Daniela, Ukropec Jozef, Sedláková Barbora, Riecanský Igor, Krizanová Ol'ga, Seböková Elena, Dobríková Martina, Klimes Iwar, Tkác Ivan

Abstract excerpt

BACKGROUND: HDL-cholesterol (HDL-C) is a recognized athero-protective factor and low levels of HDL-C occur frequently in patients with coronary artery disease. Regulation of HDL-C level most probably results from the interaction of genes involved in lipoprotein metabolism and also from non-genetic factors. We studied associations and interactions among HindIII polymorphisms of the lipoprotein lipase gene LPL and...

Topics

Aged
Alleles
Cholesterol, HDL
Coronary Artery Disease
Cross-Sectional Studies
Deoxyribonuclease HindIII
Female
Gene Frequency
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Hypercholesterolemia

Lipoprotein Lipase

Male

Middle Aged

Polymorphism, Genetic

Risk Factors

Slovakia

Source

Open in PubMed

Identifiers

PMID: 17721767
DOI: 10.1007/s00508-007-0824-1

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