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Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome

16 Dec 2005

Abstract excerpt

The genome of Bunyamwera virus (BUN; family Bunyaviridae, genus Orthobunyavirus) comprises three segments of negative-sense, single-stranded RNA. The RNA segments are encapsidated by the viral nucleocapsid (N) protein and form panhandle-like structures through interaction of complementary sequences at their 5' and 3' termini. Transcription and replication of a BUN genome analogue (minireplicon), comprising the...

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PMID: 16361430
DOI: 10.1099/vir.0.81227-0

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