Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A life-course approach to the aetiology of late-onset dementias.

The Lancet. Neurology - 1 Jan 2006

Whalley Lawrence J, Dick Finlay D, McNeill Geraldine

Abstract excerpt

Substantial progress has been made in the understanding of the neurobiology of dementias, but comprehensive causal models are not available. Genetic and environmental factors probably interact to determine vulnerability to the dementias. The life-course approach to age-related diseases, when systematically applied to the dementias, provides opportunities to identify the nature and timing of environmental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Age of Onset
Share to Dementia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environment

Share to Epigenesis, Genetic

Share to Fetal Development

Share to Fetal Growth Retardation

Share to Sex Factors

Source

Identifiers

PMID: 16361026
DOI: 10.1016/S1474-4422(05)70286-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A life-course approach to the aetiology of late-onset dementias.PMID 16361026Read ↗

Introduction: genetic determinants of mid- and late-life dementias.Semantic proximity Read ↗

Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm.Semantic proximity Read ↗

The genetics of dementia in late life.Semantic proximity Read ↗

Early-Life Environment Influence on Late-Onset Alzheimer’s DiseaseSemantic proximity Read ↗

The evolution of Alzheimer disease, the reproductive schedule, and apoE isoforms☆Semantic proximity Read ↗

What is a genetic cause? The example of Alzheimer's Disease.Semantic proximity Read ↗

Applying Epigenetics to Alzheimer’s Disease via the Latent Early–life Associated Regulation (LEARn) ModelSemantic proximity Read ↗

Environmental factors in the development and progression of late-onset Alzheimer’s diseaseSemantic proximity Read ↗

Early-life risk factors and the development of Alzheimer's disease.Semantic proximity Read ↗

Role of early life exposure and environment on neurodegeneration: implications on brain disordersSemantic proximity Read ↗

Evolution of senescence: Alzheimer's disease and evolution.Semantic proximity Read ↗

Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.