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Article

Dimerization and enzymatic activity of fungal 17beta-hydroxysteroid dehydrogenase from the short-chain dehydrogenase/reductase superfamily.

BMC biochemistry - 16 Dec 2005

Kristan Katja, Deluca Dominga, Adamski Jerzy, Stojan Jure, Rizner Tea Lanisnik

Abstract excerpt

BACKGROUND: 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus (17beta-HSDcl) is a member of the short-chain dehydrogenase/reductase (SDR) superfamily. SDR proteins usually function as dimers or tetramers and 17beta-HSDcl is also a homodimer under native conditions. RESULTS: We have investigated here which secondary structure elements are involved in the dimerization of 17beta-HSDcl and...

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Identifiers

PMID: 16359545
DOI: 10.1186/1471-2091-6-28
PMCID: PMC1326212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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