Article
UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man.
Biology of reproduction - 1 Apr 2006
Rohozinski Jan, Lamb Dolores J, Bishop Colin E
Abstract excerpt
In the mouse, Utp14b is a retrogene transposed to an intron of Acsl3 (long-chain-fatty-acid coenzyme A ligase 3) on mouse chromosome 1. It represents a copy of Utp14a, a ubiquitously expressed, X-linked gene involved in 18S rRNA synthesis. The Utp14b is specifically expressed in male germ cells and, when mutated in the jsd (juvenile spermatogonial depletion) mouse, results in early spermatogenic arrest and male...
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