Use of batch and fed-batch fermentation for studies on the variation of glutathione content and its influence on the genotoxicity of methyl-nitro-nitrosoguanidine in yeast.

doi:10.1093/mutage/7.1.25

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Article

Use of batch and fed-batch fermentation for studies on the variation of glutathione content and its influence on the genotoxicity of methyl-nitro-nitrosoguanidine in yeast.

Mutagenesis - 1 Jan 1992

Berthe-Corti L, Hulsch R, Nevries U, Eckardt-Schupp F

Abstract excerpt

We have applied fermenter techniques to analyse the variations of glutathione (GSH) content in cultures of the diploid strain D7 of Saccharomyces cerevisiae. Choosing various experimental conditions of controlled batch and fed-batch fermentation we give evidence that the GSH levels of the yeast c...

Topics

Fermentation
Glucose
Glutathione
Methylnitronitrosoguanidine
Mutagenicity Tests
Mutation
Saccharomyces cerevisiae

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