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Article

MLH1 and MSH2 mutations in Colombian families with hereditary nonpolyposis colorectal cancer (Lynch syndrome)--description of four novel mutations.

Familial cancer - 1 Jan 2005

Giraldo Alejandro, Gómez Andrea, Salguero Gustavo, García Herbert, Aristizábal Fabio, Gutiérrez Oscar, Angel Luis Alberto, Padrón Jorge, Martínez Carlos, Martínez Humberto, Malaver Omar, Flórez Luis, Barvo Rosa

Abstract excerpt

This study searched for mutations in the MLH1 and MSH2 genes in 23 unrelated Colombian families with suspected hereditary nonpolyposis colorectal cancer (HNPCC). The families were grouped according to the fulfillment of the Amsterdam II criteria or the Bethesda guidelines. We screened all proband...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Share to MutL Protein Homolog 1

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Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 16341804
DOI: 10.1007/s10689-005-4523-7

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16341804-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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