Article
The Drosophila fused lobes gene encodes an N-acetylglucosaminidase involved in N-glycan processing.
The Journal of biological chemistry - 24 Feb 2006
Léonard Renaud, Rendic Dubravko, Rabouille Catherine, Wilson Iain B H, Préat Thomas, Altmann Friedrich
Abstract excerpt
Most processed, e.g. fucosylated, N-glycans on insect glycoproteins terminate in mannose, yet the relevant modifying enzymes require the prior action of N-acetylglucosaminyltransferase I. This led to the hypothesis that a hexosaminidase acts during the course of N-glycan maturation. To determine whether the Drosophila melanogaster genome indeed encodes such an enzyme, a cDNA corresponding to fused lobes (fdl), a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.