Article
Gene therapy of the typical multidrug resistance phenotype of cancers: a new hope?
Seminars in oncology - 1 Dec 2005
Labialle Stëphane, Dayan Guila, Michaud Mickaél, Barakat Stëphane, Rigal Dominque, Baggetto Loris G
Abstract excerpt
The multidrug resistance (MDR) phenotype of cancers has generated a large amount of research, owing to its constant fatal clinical outcome. Many studies have focused on the discovery of chemomodulators; however, in spite of this huge effort, the side effects that these products induce, and their additive toxicity when used in the presence of anticancer drugs, have led to the disaffection of the pharmaceutical...
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