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Article

Genotypes of the UCP1 gene polymorphisms and cardiometabolic diseases: A multifactorial study of association with disease probability.

Biochimie - 1 Mar 2024

Pravednikova Anna E, Nikitich Antonina, Witkowicz Agata, Karabon Lidia, Flouris Andreas D, Vliora Maria, Nintou Eleni, Dinas Petros C, Szulińska Monika, Bogdański Paweł, Metsios George S, Kerchev Victor V, Yepiskoposyan Levon, Bylino Oleg V, Larina Svetlana N, Shulgin Boris, Shidlovskii Yulii V

Abstract excerpt

Cardiometabolic diseases (CMDs) are complex disorders with a heterogenous phenotype, which are caused by multiple factors including genetic factors. Single nucleotide polymorphisms (SNPs) rs45539933 (p.Ala64Thr), rs10011540 (c.-112A>C), rs3811791 (c.-1766A>G), and rs1800592 (c.-3826A>G) in the UCP1 gene have been analyzed for association with CMDs in many studies providing controversial results. However, previous...

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Alleles
Cardiovascular Diseases
Genetic Predisposition to Disease
Genotype
Ion Channels
Polymorphism, Single Nucleotide
Risk Factors
Uncoupling Protein 1

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PMID: 37863280
DOI: 10.1016/j.biochi.2023.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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