Article
The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis.
Developmental biology - 15 Jan 2006
Yu Juehua, Starr Daniel A, Wu Xiaohui, Parkhurst Susan M, Zhuang Yuan, Xu Tian, Xu Rener, Han Min
Abstract excerpt
During late stages of Drosophila oogenesis, the cytoplasm of nurse cells in the egg chamber is rapidly transferred ("dumped") to oocytes, while the nurse cell nuclei are anchored by a mechanism that involves the actin cytoskeleton. The factors that mediate this interaction between nuclei and actin cytoskeleton are unknown. MSP-300 is the likely Drosophila ortholog of the mammalian Syne-1 and -2 and C. elegans...
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