Article
Concurrent expression of aryl hydrocarbon receptor and CYP1A1 but not CYP1A1 MspI polymorphism is correlated with gastric cancers raised in Dalian, China.
Cancer letters - 28 Aug 2006
Ma Jing-Xin, Zhang Kai-Li, Liu Xu, Ma Yan-Lu, Pei Li-Na, Zhu Yi-Fang, Zhou Lei, Chen Xiao-Yan, Kong Qing-You, Li Hong, Liu Jia
Abstract excerpt
The frequency of cancer-associated m2m2- (C-) genotype of CYP1A1 and the factors contributing to the increased CYP1A1 expression in gastric cancers (GCs) are largely unknown. To address theses issues, PCR-restriction fragment length polymorphism (PCR-RFLP) was performed to elucidate the MspI polymorphism in 60 GC cases and 57 normal donor samples. The frequencies of m1m1-, m1m2- and m2m2-genotype were 43.3, 45...
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