Article
Genomewide scan for real-word reading subphenotypes of dyslexia: novel chromosome 13 locus and genetic complexity.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2006
Igo Robert P, Chapman Nicola H, Berninger Virginia W, Matsushita Mark, Brkanac Zoran, Rothstein Joseph H, Holzman Ted, Nielsen Kathleen, Raskind Wendy H, Wijsman Ellen M
Abstract excerpt
Dyslexia is a common learning disability exhibited as a delay in acquiring reading skills despite adequate intelligence and instruction. Reading single real words (real-word reading, RWR) is especially impaired in many dyslexics. We performed a genome scan, using variance components (VC) linkage analysis and Bayesian Markov chain Monte Carlo (MCMC) joint segregation and linkage analysis, for three quantitative...
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