Article
Genome scan of a nonword repetition phenotype in families with dyslexia: evidence for multiple loci.
Behavior genetics - 1 Sept 2008
Brkanac Zoran, Chapman Nicola H, Igo Robert P, Matsushita Mark M, Nielsen Kathleen, Berninger Virginia W, Wijsman Ellen M, Raskind Wendy H
Abstract excerpt
To understand the genetic architecture of dyslexia and identify the locations of genes involved, we performed linkage analyses in multigenerational families using a phonological memory phenotype--Nonword Repetition (NWR). A genome scan was first performed on 438 people from 51 families (DS-1) and linkage was assessed using variance components (VC), Bayesian oligogenic (BO), and parametric analyses. For...
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