Article
[Interleukin 10 gene -627 polymorphisms in Chinese patients with early-onset coronary heart disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2005
Wang Yun-ying, Yu Xin-juan, Wang Pei-lin, Bao Zhen-min
Abstract excerpt
OBJECTIVE: To investigate the relationship between interleukin 10 (IL10) gene -627 polymorphisms and serum IL10 level and early-onset coronary heart disease (CHD). METHODS: The genotype and allele frequency of IL10 gene -627 site was assayed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). DNA samples were obtained from 163 patients with CHD and 112 controls. Serum IL10 level was...
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