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Article

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes.

Proceedings of the National Academy of Sciences of the United States of America - 24 Nov 1998

Braun A, Hoffmann J A, Meister M

Abstract excerpt

We have analyzed the Drosophila immune response in domino mutant larvae, which are devoid of blood cells. The domino mutants have a good larval viability, but they die as prepupae. We show that, on immune challenge, induction of the genes encoding antimicrobial peptides in the fat body is not affected significantly in the mutant larvae, indicating that hemocytes are not essential in this process. The hemocoele of...

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Identifiers

PMID: 9826701
DOI: 10.1073/pnas.95.24.14337
PMCID: PMC24374

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