Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes.

doi:10.1073/pnas.95.24.14337

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Article

Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes.

Proceedings of the National Academy of Sciences of the United States of America - 24 Nov 1998

Braun A, Hoffmann J A, Meister M

Abstract excerpt

We have analyzed the Drosophila immune response in domino mutant larvae, which are devoid of blood cells. The domino mutants have a good larval viability, but they die as prepupae. We show that, on immune challenge, induction of the genes encoding antimicrobial peptides in the fat body is not aff...

Topics

Adipose Tissue
Animals
Candida
Drosophila
Escherichia coli
Genotype
Hemocytes
Larva
Melanins
Micrococcus luteus
Spores, Fungal

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