Article
c-kit Expression and mutations in peripheral T cell lymphomas, except for extra-nodal NK/T cell lymphomas.
Leukemia & lymphoma - 1 Feb 2006
Choe Yee Soo, Kim Jong Gwang, Sohn Sang Kyun, Kim Dong Hwan, Baek Jin Ho, Lee Kyu Bo, Do Young Rok, Kwon Ki Young, Song Hong Suk, Lee Myung Hoon, Park Tae In
Abstract excerpt
The present study evaluated the expression and mutations of c-kit in peripheral T-cell lymphomas (PTCLs), except for extra-nodal NK/T cell lymphomas, as a potential target for treatment with imatinib mesylate. Fifty-two patients diagnosed with PTCLs (peripheral T-cell lymhoma, unspecified, 38 cases; angioimmunoblastic T-cell, 7 cases; anaplastic large cell, 7 cases) were enrolled. The immunohistochemistry was...
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