Article
Overexpression of the epidermal growth factor receptor confers migratory properties to nonmigratory postnatal neural progenitors.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Nov 2005
Aguirre Adan, Rizvi Tilat A, Ratner Nancy, Gallo Vittorio
Abstract excerpt
Approaches to successful cell transplantation therapies for the injured brain involve selecting the appropriate neural progenitor type and optimizing the efficiency of the cell engraftment. Here we show that epidermal growth factor receptor (EGFR) expression enhances postnatal neural progenitor migration in vitro and in vivo. Migratory NG2-expressing (NG2+) progenitor cells of the postnatal subventricular zone...
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