Article
SapT, a lanthionine-containing peptide involved in aerial hyphae formation in the streptomycetes.
Molecular microbiology - 1 Dec 2005
Kodani Shinya, Lodato Michael A, Durrant Marcus C, Picart Francis, Willey Joanne M
Abstract excerpt
The developmentally complex soil microbe Streptomyces tendae secretes a hydrophobic peptide that restored to developmental mutants of S. coelicolor the ability to raise aerial hyphae. The S. tendae peptide, SapT, has a lantibiotic structure and molecular modelling predicts that it is amphiphilic, making it structurally and functionally similar to the SapB peptide produced by S. coelicolor. However, SapT, which...
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