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Article

Different alleles of the response regulator gene bldM arrest Streptomyces coelicolor development at distinct stages.

Molecular microbiology - 1 Jun 2000

Molle V, Buttner M J

Abstract excerpt

whiK was one of five new whi loci identified in a recent screen of NTG-induced whi mutants and was defined by three mutants, R273, R318 and R655. R273 and R318 produce long, tightly coiled aerial hyphae with frequent septation. In contrast, R655 shows a more severe phenotype; it produces straight, undifferentiated aerial hyphae with very rare short chains of spores. Subcloning and sequencing showed that whiK...

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PMID: 10931278
DOI: 10.1046/j.1365-2958.2000.01977.x

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