Article
Modeling genome evolution with a diffusion approximation of a birth-and-death process.
Bioinformatics (Oxford, England) - 1 Nov 2005
Karev Georgy P, Berezovskaya Faina S, Koonin Eugene V
Abstract excerpt
MOTIVATION: In our previous studies, we developed discrete-space birth, death and innovation models (BDIMs) of genome evolution. These models explain the origin of the characteristic Pareto distribution of paralogous gene family sizes in genomes, and model parameters that provide for the evolutio...
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