Article
Salmonella inhibit T cell proliferation by a direct, contact-dependent immunosuppressive effect.
Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 2005
van der Velden Adrianus W M, Copass Michael K, Starnbach Michael N
Abstract excerpt
Dendritic cells (DC) are of central importance in the initiation of T cell-mediated adaptive immunity because these professional phagocytes internalize, process, and present microbial antigens to T lymphocytes. T lymphocytes have a pivotal role in controlling and clearing infection with intracellular pathogens through cytokine production. T lymphocytes also can mediate direct lysis of infected cells or activate B...
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