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Article

RAGE polymorphisms and the heritability of insulin resistance: the Leeds family study.

Diabetes & vascular disease research - 1 Feb 2005

Sullivan Clair M, Futers T Simon, Barrett Jennifer H, Hudson Barry I, Freeman Mark S, Grant Peter J

Abstract excerpt

UNLABELLED: Activation of the receptor for advanced glycation end-products (RAGE) leads to a cascade of pro-inflammatory and pro-coagulant responses which are important in the pathogenesis of the vascular complications of diabetes mellitus. It is known that pro-inflammatory mechanisms underpin the development of type 2 diabetes. Our hypothesis is that RAGE may be involved in the evolution of insulin resistance in...

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Identifiers

PMID: 16305072
DOI: 10.3132/dvdr.2005.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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