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Article

Molecular Pathogenesis of MDS

1 Jan 2005

Abstract excerpt

Clonal disorders of hematopoiesis, such as myelodysplastic syndromes (MDS) and myeloproliferative diseases (MPD), affect both hematopoietic stem cells and progenitor cells within the erythroid, platelet and granulocytic lineages and can have devastating consequences in children and adults. The genetic features of these diseases often include clonal, nonrandom chromosomal deletions (e.g., 7q-, 5q-, 20q-, 6q-, 11q-...

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Identifiers

PMID: 16304374
DOI: 10.1182/asheducation-2005.1.156

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