Article
Codon and amino acid usage in two major human pathogens of genus Bartonella--optimization between replicational-transcriptional selection, translational control and cost minimization.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Jan 2005
Das Sabyasachi, Paul Sandip, Chatterjee Sanjib, Dutta Chitra
Abstract excerpt
Intra-genomic variation in synonymous codon and amino acid usage in two human pathogens Bartonella henselae and B. quintana has been carried out through multivariate analysis. Asymmetric mutational bias, coupled with replicational-transcriptional selection, has been identified as the prime selection force behind synonymous codon selection--a characteristic of the genus Bartonella, not exhibited by any other...
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