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Article

Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase.

Arthritis research & therapy - 1 Jan 2005

Bockermann Robert, Schubert David, Kamradt Thomas, Holmdahl Rikard

Abstract excerpt

Antibodies specific for glucose-6-phosphate isomerase (G6PI) from T-cell receptor transgenic K/BxN mice are known to induce arthritis in mice, and immunization of DBA/1 mice with G6PI led to acute arthritis without permanent deformation of their joints. Because rheumatoid arthritis is a chronic disease, we set out to identify the capacity of G6PI to induce chronic arthritis in mice. Immunization with recombinant...

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Source

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Identifiers

PMID: 16277685
DOI: 10.1186/ar1829
PMCID: PMC1297579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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