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Article

Identification of a basolateral sorting signal within the cytoplasmic domain of the interleukin-6 signal transducer gp130.

Cellular signalling - 1 Aug 2006

Doumanov Jordan A, Daubrawa Merle, Unden Heike, Graeve Lutz

Abstract excerpt

Interleukin-6-type cytokine receptors are expressed in polarized cells such as hepatocytes and intestinal cells. For the interleukin-6-receptor gp80 and its signal transducer gp130, a preferential basolateral localization was demonstrated in Madin-Darby canine kidney (MDCK) cells and two basolateral sorting signals were identified within the cytoplasmic domain of gp80. The cytoplasmic tail of gp130 is responsible...

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Identifiers

PMID: 16274960
DOI: 10.1016/j.cellsig.2005.09.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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