Article
Mutations in a conserved replication protein suppress transcriptional gene silencing in a DNA-methylation-independent manner in Arabidopsis.
Current biology : CB - 8 Nov 2005
Kapoor Avnish, Agarwal Manu, Andreucci Andrea, Zheng Xianwu, Gong Zhizhong, Hasegawa Paul M, Bressan Ray A, Zhu Jian-Kang
Abstract excerpt
Mutations in the DNA glycosylase/lyase ROS1 cause transcriptional silencing of the linked RD29A-LUC and 35S-NPTII transgenes in Arabidopsis. We report here that mutations in the Arabidopsis RPA2 locus release the silencing of 35S-NPTII but not RD29A-LUC in the ros1 mutant background. The rpa2 mutation also leads to enhanced expression of some transposons. Neither DNA methylation nor siRNAs at any of the...
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