Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes.

doi:10.1176/appi.ajp.162.11.2101

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Article

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes.

The American journal of psychiatry - 1 Nov 2005

Schulze Thomas G, Ohlraun Stephanie, Czerski Piotr M, Schumacher Johannes, Kassem Layla, Deschner Monika, Gross Magdalena, Tullius Monja, Heidmann Vivien, Kovalenko Svetlana, Jamra Rami Abou, Becker Tim, Leszczynska-Rodziewicz Anna, Hauser Joanna, Illig Thomas, Klopp Norman, Wellek Stefan, Cichon Sven, Henn Fritz A, McMahon Francis J, Maier Wolfgang, Propping Peter, Nöthen Markus M, Rietschel Marcella

Abstract excerpt

OBJECTIVE: The authors previously reported an association between the D-amino acid oxidase activator (DAOA)/G30 locus and both schizophrenia and bipolar affective disorder. Given the presumed role of DAOA/G30 in the neurochemistry of psychosis and its localization in a schizophrenia and bipolar affective disorder linkage region (13q34), it was hypothesized that the bipolar affective disorder finding would be...

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PMID: 16263850
DOI: 10.1176/appi.ajp.162.11.2101

Genes

DAOA

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