Article
Tachyphylaxis to beta2-agonists in Spanish asthmatic patients could be modulated by beta2-adrenoceptor gene polymorphisms.
Respiratory medicine - 1 Jun 2006
Tellería Juan Jose, Blanco-Quirós Alfredo, Muntión Sandra, Antonio Garrote Jose, Arranz Eduardo, Armentia Alicia, Díez Ignacio, Castro Jesús
Abstract excerpt
BACKGROUND: The study of determinants of asthma is a subject of much interest currently, especially the pharmacogenetic aspects of asthma management. Genetic polymorphisms affecting amino-acids at positions 16 and 27 within beta(2)-adrenoceptor (beta(2)AR) gene have been implicated in the asthma...
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