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Article

Tachyphylaxis to beta2-agonists in Spanish asthmatic patients could be modulated by beta2-adrenoceptor gene polymorphisms.

Respiratory medicine - 1 Jun 2006

Tellería Juan Jose, Blanco-Quirós Alfredo, Muntión Sandra, Antonio Garrote Jose, Arranz Eduardo, Armentia Alicia, Díez Ignacio, Castro Jesús

Abstract excerpt

BACKGROUND: The study of determinants of asthma is a subject of much interest currently, especially the pharmacogenetic aspects of asthma management. Genetic polymorphisms affecting amino-acids at positions 16 and 27 within beta(2)-adrenoceptor (beta(2)AR) gene have been implicated in the asthma phenotypes and influence on the variability observed in response to use of bronchodilator agents used in the treatment...

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Identifiers

PMID: 16263254
DOI: 10.1016/j.rmed.2005.09.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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