Article
The common variant N372H in BRCA2 gene may be associated with idiopathic male infertility with azoospermia or severe oligozoospermia.
European journal of obstetrics, gynecology, and reproductive biology - 1 Jan 2006
Zhoucun A, Zhang Sizhong, Yang Yuan, Ma Yongxin, Zhang Wei, Lin Li
Abstract excerpt
OBJECTIVE: To explore the possible association between the common single nucleotide polymorphism N372H in human breast cancer susceptibility gene 2 (BRCA2) and the idiopathic male infertility with azoospermia or severe oligozoospermia. STUDY DESIGN: The study included 240 infertile patients with idiopathic azoospermia or severe oligozoospermia and 250 fathered controls. The allele and genotype frequencies of the...
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