Article
Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants.
Genome research - 1 Nov 2005
Lawrence Robert, Evans David M, Morris Andrew P, Ke Xiayi, Hunt Sarah, Paolucci Marta, Ragoussis Jiannis, Deloukas Panos, Bentley David, Cardon Lon R
Abstract excerpt
As part of a recent high-density linkage disequilibrium (LD) study of chromosome 20, we obtained genotypes for approximately 30,000 SNPs at a density of 1 SNP/2 kb on four different population samples (47 CEPH founders; 91 UK unrelateds [unrelated white individuals of western European ancestry]; 97 African Americans; 42 East Asians). We observed that approximately 50% of SNPs had at least one genetically...
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