Article
Transgenic manipulation of the ubiquitin-proteasome system.
Essays in biochemistry - 1 Jan 2005
Gray Douglas A
Abstract excerpt
The transgenic approach has been used in model systems from yeast to mammals to address basic research questions, and to achieve agricultural, pharmaceutical or industrial objectives. In basic research, transgenic organisms have generated novel observations that could not have been obtained otherwise. This chapter concentrates on the use of transgenics in deciphering the operation of the UPS (ubiquitin-proteasome...
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