Article
Transgenic mice as models for heritable diseases.
Annals of medicine - 1 Apr 1992
Metsäranta M, Vuorio E
Abstract excerpt
The development of methods for introduction of foreign DNA stably into genome of experimental animals has opened new possibilities to study the effects of mutations in complex gene-protein systems at the level of the entire organism. Information from such experiments is directly applicable to understanding of pathogenetic mechanisms in hereditary diseases and to designing of new therapeutic approaches. Techniques...
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