Increased expression of the ska gene in emm49-genotyped Streptococcus pyogenes strains isolated from patients with severe invasive streptococcal infections.

Abstract excerpt

Since 2000, emm49-genotyped Streptococcus pyogenes strains have been isolated from patients with severe invasive group A streptococcal infections in Japan, although they had not been isolated before 1999. We compare the characteristics of these strains with those of strains isolated from patients with non-invasive infections. SmaI-digested pulsed-field gel electrophoresis profiles of the isolates were almost...

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